ToolkitNot tested

ClawBio

Bioinformatics Skill library with local CLI and agent integrations

ClawBio combines a local Python bioinformatics library and CLI with agent-routable Skills for genomics, pharmacogenomics, ancestry, single-cell analysis, metagenomics, and related biomedical workflows.

For: Research Postgraduate Students, Doctoral Researchers, Academic Researchers

GitHub stars
1,039
Licence
MIT
Source updated
14 Jul 2026
Access
Publicly available

What this resource does

Core uses

About this resource

ClawBio combines a local Python bioinformatics library and CLI with agent-routable Skills for genomics, pharmacogenomics, ancestry, single-cell analysis, metagenomics, and related biomedical workflows.

This page groups representative academic components by task; review the repository for the complete inventory.

01

Variant and pharmacogenomic analysis

Provides Skills for variant annotation, rare-variant reporting, pharmacogenomic interpretation, and related genomic reports.

Typical inputs
Compatible VCF or supported genotype input; Selected analysis and output location
Output
A component-dependent variant or pharmacogenomic report and supporting artifacts.

Best for: Research analysis of genomic variants with appropriate domain review.

Components for this task

variant-annotation

Annotates genomic variants through the documented local workflow.

pharmgx-reporter

Creates a pharmacogenomic report from supported genetic inputs.

02

RNA and single-cell workflows

Includes components for RNA-seq differential expression, single-cell orchestration, embedding, and related analysis.

Typical inputs
Compatible count matrices, metadata, or sequencing project files
Output
A component-dependent analysis directory, tables, figures, or report.

Best for: Bioinformatics projects with prepared data and a defined analysis question.

Components for this task

rnaseq-de

Runs an RNA-seq differential-expression workflow.

scrna-orchestrator

Coordinates a single-cell RNA-seq analysis workflow.

03

Reproducible local Skill execution

Runs named Skills through a local CLI or Python API and records inspectable files and commands.

Typical inputs
Skill name, input arguments, and output directory
Output
Local files, reports, logs, and replay information for the selected Skill.

Best for: Researchers who want a direct local route without a chat interface.

Component for this task

claw-metagenomics

Runs a metagenomics workflow through a local ClawBio Skill.

Suggested workflow requests (2)

Run the pharmacogenomics demo and save its report to a new output directory.

List the available ClawBio Skills and show which inputs each selected Skill expects.

Adapted into complete requests from official trigger wording in README.md.

Use boundaries

Limits and checks

Sensitive genomic data

Files or configured services may expose highly sensitive data.

Use approved local environments, minimise identifiers, and check whether the selected Skill calls a hosted API.

Reference and method changes

Results can differ by version or become outdated.

Record versions and reference data and review interpretation with a domain specialist.

Optional hosted services

Data handling, availability, and cost differ from the local workflows.

Read the selected SKILL.md and provider terms before sending data.

More boundaries
  • Do not use a ClawBio workflow with an unsupported biological file type or without the required reference data and tools.
  • A generated genomic or pharmacogenomic report is not a clinical diagnosis or treatment recommendation.
  • Local replay artifacts do not by themselves prove that a biological method or result is valid.
Technical details
Resource type
Toolkit
Author or maintainer
ClawBio
Latest release
v0.5.2: pip install clawbio (v0.5.2)
Source last updated
14 Jul 2026
Last verified
15 Jul 2026
Documented applications
Claude Code, OpenClaw, ClawBio CLI and Python library, RoboTerri
Documented AI models
Claude, ChatGPT, Ollama-hosted models
Licence
MIT
Access
Publicly available
Additional costs
Platform terms or usage limits may apply. API usage fees may apply for selected components. External services, software, compute, or data access may have separate costs.
Skill instruction language
English
Documentation language
English
Repository languages
Python, Markdown
Dependencies
Python 3.11 or later; Skill-specific Python packages, bioinformatics tools, reference data, or hosted APIs
Review status
Not tested

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Related resources

Install ClawBio